The bones of the hand and wrist provide the body with support and flexibility to manipulate objects in many different ways. Each hand contains 27 distinct bones that give the hand an incredible range and precision of motion. The forearm’s ulna and radius support the many muscles that manipulate the bones of the hand and wrist. Rotation of the radius around the ulna results in the supination and pronation of the hand. These bones also form the flexible wrist.
Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage. Drug-induced liver injury is a cause of acute and chronic liver disease. The liver plays a central role in transforming and clearing chemicals and is susceptible to the toxicity from these agents. Certain medicinal agents, when taken in overdoses and sometimes even when introduced within therapeutic ranges, may injure the organ. Other chemical agents, such as those used in laboratories and industries, natural chemicals (e.g., microcystins) and herbal remedies can.
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